EduKon.net » eBooks » Carbonic Anhydrase as Drug Target: Thermodynamics and Structure of Inhibitor Binding

 

Carbonic Anhydrase as Drug Target: Thermodynamics and Structure of Inhibitor Binding

Author: bestrelease

Carbonic Anhydrase as Drug Target: Thermodynamics and Structure of Inhibitor Binding
English | ISBN: 3030127788 | 2019 | 353 pages | EPUB, PDF | 59 MB + 19 MB

"Carbonic Anhydrase as Drug Target: Thermodynamics and Structure of Inhibitor Binding"

HI-SPEED DOWNLOAD
Free 300 GB with Full DSL-Broadband Speed!



Carbonic Anhydrase as Drug Target: Thermodynamics and Structure of Inhibitor Binding
English | ISBN: 3030127788 | 2019 | 353 pages | EPUB, PDF | 59 MB + 19 MB

This book offers deep insights into the thermodynamics and molecular structures of the twelve catalytically active isoforms of human carbonic anhydrase (CA) with a particular focus on inhibitor binding for drug design. X-ray crystallographic structures in combination with enzyme kinetic testing provide information on the interaction of CAs and their inhibitors, knowledge which is crucial for rational drug design. CAs are zinc carrying enzymes that catalyse the reversible interconversion of carbon dioxide and bicarbonate and are involved in numerous cellular processes. They are therefore a common target for drugs. The suppression of CA activities through inhibitory compounds has found application for example in diuretics and in glaucoma therapy. In this book methods used to determine binding thermodynamics of inhibitory compounds (Isothermal titration calorimetry, Fluorescent thermal shift assay/differential scanning fluorimetry and others) will be compared in detail. Also types and chemical synthesis of CA inhibitors, the use of antibodies against CAs as well as inhibitor application in animals are discussed.


P A S S W O R D    P R O T E C T E D ! 
PASSWORD WILL BE PUBLISHED HERE TOMORROW!
 PLEASE ADD PAGE TO YOUR FAVORITS

Free 300 GB with 10 GB High-Speed(No Password BACKUP)


Hide Your IP & Protect Your Privacy!
Get Your 15 Day Free Trial Now.

Category: eBooks


Tags: Carbonic, Anhydrase, Drug, Target, Thermodynamics, Structure, Inhibitor, Binding

Carbonic Anhydrase as Drug Target: Thermodynamics and Structure of Inhibitor Binding Fast Download via Rapidshare Upload Filehosting Megaupload, Carbonic Anhydrase as Drug Target: Thermodynamics and Structure of Inhibitor Binding Torrents and Emule Download or anything related.
Information
Comment on the news site is possible only within (days) days from the date of publication.